Areas of Interest
I am interested in the physics of biological molecules in nano-scale environments. In particular, DNA can be efficiently manipulated by confining it to channels with a cross-section that is on the order of the DNA persistence length (50 nm). My research includes novel techniques in nanobiotechnology, using nanoconfined DNA to solve biological puzzles, and exploring polymer physics with DNA as the model system. The goal of my research is to give medics and biologists tools which can help them do their jobs cheaper, better, and faster. (I am aware that some people think attaining all three is impossible)
Recent Publications
Near-field enhanced ultraviolet resonance Raman spectroscopy using aluminum bow-tie nano-antenna.
Ling Li, Shuang Fang Lim, Alexander A. Puretzky, Robert Riehn, and H. D. Hallen,
Applied Physics Letters 101 (11), 2012, doi:10.1063/1.4746747
Fluctuation modes of nanoconfined DNA.
Alena Karpusenko, Joshua H. Carpenter, Chunda Zhou, Shuang Fang Lim, Junhan Pan, and Robert Riehn,
Journal of Applied Physics, 2012, art. no. 024701,doi:10.1063/1.3675207
Collapse of DNA in ac electric fields.
Chunda Zhou, Walter W. Reisner, Rory J. Staunton, Amir Ashan, Robert H. Austin, and Robert Riehn,
Physical Review Letters, 2011, 106 (24), art. no. 248103.
DOI: 10.1103/PhysRevLett.106.248103
Density fluctuations dispersion relationship for a polymer confined to a nanotube.
Joshua H. Carpenter, Alena Karpusenko, Junhan Pan, Shuang Fang Lim, and Robert Riehn,
Applied Physics Letters, 2011, 98, 253704, doi:10.1063/1.3602922
DNA Methylation Profiling in Nanochannels.
Shuang Fang Lim, Alena Karpusenko, John J. Sakon, Joseph A. Hook, Tyra A. Lamar, Robert Riehn,
Biomicrofluidics. Accepted for publication. 2011, doi:10.1063/1.3613671
DNA condensation by field-induced non-equilibrium noise.
Bruinsma RF, Riehn R,
Chemphyschem., 2009, 10 (16), 2871-5.(full)
Stretching chromatin through confinement.
Diana E. Streng, Shuang Fang Lim, Junhan Pan, Alena Karpusenka and Robert Riehn,
Lab on a Chip, 9, 2772 - 2774,(2009) DOI: 10.1039/b909217j, (full)
Upconverting nanophosphors for bioimaging.
Shuang Fang Lim, Robert Riehn, Chih-kuan Tung, William S Ryu, Rui Zhuo, Joanna Dalland and Robert H Austin,
Nanotechnology 20 No 40 (7 October 2009) 405701 (full)
Complementary metal oxide semiconductor compatible fabrication and characterization of parylene-C covered nanofluidic channels with integrated nanoelectrodes.
Tung CK, Riehn R, Austin RH.
BIOMICROFLUIDICS 3(3), 031101 (2009) (full)
Single molecule correlation spectroscopy in continuous flow mixers with zero-mode waveguides.
D. Liao, P. Galajda, R. Riehn, R. Ilic, J. L. Puchalla, H. G. Yu, H. G. Craighead and R. H. Austin,
Optics Express, 16, 10077-10090. (2008) (full)
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